Distributing Medical Wound Care Innovations
A new innovative dimension of open wound
Introducing PATHELEN® Wound Powder
PATHELEN® Wound Powder is a combination of active ingredients, which are made of different pyrogenic silica, reducing the healing time of chronic wounds by eliminating the biofilm, especially multi-resistant germs and offers a cost-effective alternative to the current treatment options for wounds.
The burden of chronic wounds on the Healthcare systems
Anti-microbial resistance: a global public health problem
Antimicrobial resistance (AMR) threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses and fungi. (WHO, 2020)
Antimicrobial resistance is accelerating due to overuse of antimicrobials.
The healthcare costs are higher among those with resistant infections
“Antimicrobial resistance is a crisis that must be managed with the utmost urgency. As the world enters the ambitious new era of sustainable development, we cannot allow hard-won gains for health to be eroded by the failure of our mainstay medicines.” (Global Action plan on antimicrobial resistance, WHO report, 2015)
Antibiotics are not the answer
Wounds and the biofilm
Biofilms are composites of bacterial cells, encased in an extracellular matrix composed of hydrated polymers and debris that create a shield against the host’s immune cells
Chronic wounds represent an ideal environment for biofilm formation since the necrotic tissue and debris allow bacterial attachment
Up to 60% of chronic wounds contain a biofilm1
A biofilm impairs wound healing and is resistant to antimicrobial therapy2
PATHELEN® Wound Powder is the first ‘One-step solution’ for efficient removal of the biofilm.
PATHELEN® Wound Powder is a wound therapy that combines hydrophilic and hydrophobic pyrogenic silica. The extremely large surface structure of pyrogenic silica (1 bottle of Pathelen Wound Powder contains 2g with a surface of approx. 600m2) generates an extremely high capillary action that adsorbs wound exudate, bacterial endotoxins and in doing so, disrupts the biofilm, thereby ensuring a fast and efficient physical cleansing of the wound.
PATHELEN® Wound Powder thus “de-toxifies” and cleans the wound.
PATHELEN® Wound Powder is not antibacterial but withdraws water from a bacterial biofilm, disrupting its structure and allowing the host’s immune system to gain entry and destroy the micro-organisms present.
Woundpowder and PATHELEN®
Hybrid are the same product.
Due to its mode of action, PATHELEN® Hybrid is able to treat a WIDE range of acute and chronic wounds.
PATHELEN® Hybrid is a Medical Class I Device (CE) registered with the EMA (European Medical Agency) and the United States FDA
PATHELEN® Wound Powder has been shown to be effective against*
PATHELEN® Wound Powder works most efficiently when a biofilm is present on the wound. It should not be used if there are obvious signs of infection i.e., erythema, swelling, warmth, beyond the wound
*Based on numerous independent case studies/reports
Aerosil 300 Pharma
Aerosil R972 Pharma
Type 2 diabetes mellitus, abscess of the left tibia
Remove any bandages, plasters etc.
Apply Wound Cleaning/Debridement
Dry the wound surface with sterile gauze
Shake the 50 ml bottle for 10 seconds (the powder will grow in density)
Apply PATHELEN® Hybrid in a uniform layer with a thickness of 3 to 5 mm.
Add further treatment following point 1 to 5 after 24 hours.
7 days later
Infection eliminated. Start of active granulation
11 days later
Full coverage of the wound by granulation tissues. Start of epithelisation. Termination of Pathelen Treatment
PATHELEN® Wound Powder
Pathelen has a unique mode of action due to the presence of both hydrophilic and hydrophobic silica, which enables physical adsorption of micro-organisms, toxic bacterial proteins and exudate from the wound.
MANAGEMENT OF WOUNDS
$6,530 TO $14,6301
PATHELEN® is cost-effective & reduces healing time
In a series of 23 case studies using PATHELEN®
for various wounds including:
Average healing time*
Patient: Anonymous, 55 y.o.
Wounds were required to granulate and or were required to heal by secondary intention with epithelialization.
By day 10 of Pathelen dressings the wound had filled up with granulation tissue with remarkable wound contraction. As a result, will not require the use of a flap to cover the wound she will require a simple split thickness skin graft to cover the wound.
Patient: Jacob A., 28 y.o.
The wound was initially cleansed with normal saline and covered with iodine solution. Unfortunately, wound healing process was slow.
Dressing changes were done daily, and the wound showed drastic improvement within few days. There was no foul odour and no discharge.
Patient: Oleksii T., 41 y.o.
Patient: Oleksii T., 41 y.o.
Patient: Vasiliy S., 69 y.o.
1 year ago - laryngectomy with resection of the hypopharynx. After surgery - course of radiation therapy.
On the 4th day after surgery:
- Massive post-surgery lymphorrhea - MRSA-infected wound
-Necrosus of skin patches: defect of skin 8x10 cm - Denudation of carotid artery in the wound